Adölesan Obezitesinin Elektrokardiyografi ve Solunum Fonksiyon Testleri Üzerine Etkilerinin Değerlendirilmesi
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Original Article
P: 202-208
August 2022

Adölesan Obezitesinin Elektrokardiyografi ve Solunum Fonksiyon Testleri Üzerine Etkilerinin Değerlendirilmesi

J Curr Pediatr 2022;20(2):202-208
1. Esenler Kadın Doğum ve Çocuk Hastalıkları Hastanesi, Çocuk Sağlığı ve Hastalıkları Kliniği, İstanbul, Türkiye
2. Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Çocuk Endokrinoloji Bilim Dalı, Konya, Türkiye
3. Kütahya Sağlık Bilimleri Üniversitesi Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Çocuk Kardiyoloji Bilim Dalı, Kütahya, Türkiye
4. Kütahya Sağlık Bilimleri Üniversitesi Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Çocuk Endokrinoloji Bilim Dalı, Kütahya, Türkiye
5. Kanuni Sultan Süleyman Eğitim ve Araştırma Hastanesi, Çocuk Sağlığı ve Hastalıkları Kliniği, İstanbul, Türkiye
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Received Date: 13.01.2022
Accepted Date: 05.04.2022
Publish Date: 31.08.2022
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ABSTRACT

Introduction:

The frequency of obesity is increasing in our country and all over the world. Obesity can also increase mortality and morbidity by affecting vital vital systems such as the cardiovascular system and the respiratory system. In this sense, early recognition of obesity and prevention of complications are of vital importance. In our study, we aimed to evaluate the effects of adolescent obesity on patients with obesity and normal by compairing electrocardiography (ECG) and pulmonary function tests (PFT) findings.

Materials and Methods:

Adolescent cases between 10 and 18 years of age were included in our study. Cases were divided into three groups according to body mass index. ECG and PFT measurements of the patients were obtained and study data were obtained. The data were evaluated with SPSS package.

Results:

One hundred fifty six patients were included in our study. In our study, no significant difference was found between ECG parameters in terms of heart rate (p=0,107). When Qt and QTc groups were compared, a statistically significant difference was found (p<0.001). There was no significant difference in QT dispersion and QTc dispersion (p=0.314, p=0.624, respectively). There was a significant difference between the groups in terms of Tp-e (p<0.05). There was no significant difference between the groups in terms of Tp-e/QT ratio and Tp-e/QTc ratio (p=0.054 and p=0.058). When the values of FEV1, FEV1/FVC, PEF, FEF25-75 were compared, a statistically significant difference was found between all groups (p<0.001).

Conclusion:

In our study, we concluded that the effects of obesity on respiratory and cardiovascular system in adolescents can be determined by ECG and PFT and possible complications can be prevented.

References

1
Strüven A, Holzapfel C, Stremmel C, Brunner S. Obesity, nutrition and heart rate variability. Int J Mol Sci 2021;22:4215.
2
World Health O. Report of the commission on ending childhood obesity Geneva, Switzerland: World Health Organization;2016 [Available from: https://www.who.int/publications/i/item/9789241510066].
3
Blüher M. Obesity: Global epidemiology and pathogenesis. Nat Rev Endocrinol 2019;15:288-98.
4
Homan EA, Reyes MV, Hickey KT, Morrow JP. Clinical overview of obesity and diabetes mellitus as risk factors for atrial fibrillation and sudden cardiac death. Front Physiol 2019;9:1847.
5
Goldner B, Brandspiegel HZ, Horwitz L, Jadonath R, Cohen TJ. Utility of QT dispersion combined with the signal-averaged electrocardiogram in detecting patients susceptible to ventricular tachyarrhythmia. Am J Cardiol 1995;76:1192-4.
6
Tutar HE, Ocal B, Imamoglu A, Atalay S. Dispersion of QT and QTc interval in healthy children, and effects of sinus arrhythmia on QT dispersion. Heart 1998;80:77-9.
7
Ibisoglu E, Boyraz B, Güneş ST, Savur Ü, Naki Tekin DD, Erdoğan A, et al. Impact of surgical weight loss on novel P-wave-related variables which are nominated as predictors of atrial arrhythmias. Pacing Clin Electrophysiol 2021;44:1516-22.
8
Seyfeli E, Duru M, Kuvandik G, Kaya H, Yalcin F. Effect of obesity on P-wave dispersion and QT dispersion in women. Int J Obes 2006;30:957-61.
9
Peters U, Dixon AE, Forno E. Obesity and asthma. J Allergy Clin Immunol 2018;141:1169-79.
10
World Health O. Health for the world’s adolescents: a second chance in the second decade: summary. Geneva: World Health Organization (WHO);2014.
11
Styne DM. Childhood and adolescent obesity. Prevalence and significance. Pediatr Clin North Am 2001;48:823-54.
12
Lee EY, Yoon K-H. Epidemic obesity in children and adolescents: risk factors and prevention. Front Med 2018;12:658-66.
13
Sun GZ, Li Y, Zhou XH, Guo XF, Zhang XG, Zheng LQ, et al. Association between obesity and ECG variables in children and adolescents: A cross-sectional study. Exp Ther Med 2013;6:1455-62.
14
Salim EJ, Gunawijaya E, Yantie NPVK. Electrocardiogram abnormalities in obese adolescents. Paediatr Indones 2020;60:18-23.
15
Pidlich J, Pfeffel F, Zwiauer K, Schneider B, Schmidinger H. The effect of weight reduction on the surface electrocardiogram: a prospective trial in obese children and adolescents. Int J Obes Relat Metab Disord 1997;21:1018-23.
16
Mshui ME, Saikawa T, Ito K, Hara M, Sakata T. QT interval and QT dispersion before and after diet therapy in patients with simple obesity. Proc Soc Exp Biol Med 1999;220:133-8.
17
Horne RSC, Shandler G, Tamanyan K, Weichard A, Odoi A, Biggs SN, et al. The impact of sleep disordered breathing on cardiovascular health in overweight children. Sleep Med 2018;41:58-68.
18
Simonyi G. Electrocardiological features in obesity: the benefits of body surface potential mapping. Cardiorenal Med 2014;4:123-9.
19
Güven A, Özgen T, Güngör O, Aydın M, Baysal K. Association between the corrected QT interval and carotid artery intima-media thickness in obese children. J Clin Res Pediatr Endocrinol 2010;2:21-7.
20
Hlaing ZTT, Htway SM, Sein MT. Relationship between Corrected QT Interval (QTc) prolongation and insulin resistance in obese adult male subjects. EJMED 2021;3:42-5.
21
Gastaldelli A, Emdin M, Conforti F, Camastra S, Ferrannini E. Insulin prolongs the QTc interval in humans. Am J Physiol Regul Integr Comp Physiol 2000;279:2022-5.
22
Corbi GM, Carbone S, Ziccardi P, Giugliano G, Marfella R, Nappo F, et al. FFAs and QT intervals in obese women with visceral adiposity: effects of sustained weight loss over 1 year. J Clin Endocrinol Metab 2002;87:2080-3.
23
Zuckerman E, Yeshurun D, Goldhammer E, Shiran A. 24 h electrocardiographic monitoring in morbidly obese patients during short-term zero calorie diet. Int J Obes Relat Metab Disord 1993;17:359-61.
24
Nagy D, DeMeersman R, Gallagher D, Pietrobelli A, Zion AS, Daly D, et al. QTc interval (cardiac repolarization): lengthening after meals. Obes Res 1997;5:531-7.
25
Girola A, Enrini R, Garbetta F, Tufano A, Caviezel F. QT dispersion in uncomplicated human obesity. Obes Res 2001;9:71-7.
26
Inanir M, Sincer I, Erdal E, Gunes Y, Cosgun M, Mansiroglu AK. Evaluation of electrocardiographic ventricular repolarization parameters in extreme obesity. J Electrocardiol 2019;53:36-9.
27
Demirol M, Karadeniz C, Ozdemir R, Çoban Ş, Katipoğlu N, Yozgat Y, et al. Prolonged Tp-e Interval and Tp-e/QT ratio in children with mitral valve prolapse. Pediatr Cardiol 2016;37:1169-74.
28
Kongkiattikul L, Sritippayawan S, Chomtho S, Deerojanawong J, Prapphal N. Relationship between obesity indices and pulmonary function parameters in obese thai children and adolescents. Indian J Pediatr 2015;82:1112-6.
29
Dixon AE, Peters U. The effect of obesity on lung function. Expert Rev Respir Med 2018;12:755-67.
30
Wannamethee SG, Shaper AG, Whincup PH. Body fat distribution, body composition, and respiratory function in elderly men. Am J Clin Nutr 2005;82:996-1003.
31
Sarsan A, Alkan H, Başer S, Yıldız N, Özgen M, Ardıç F. The effect of aerobic exercise program on pulmonary function and cardiorespiratory capacity in obese women. Turk J Phys Med Rehab 2013;59:140-5.