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E-ISSN: 1308-6308 ISSN: 1304-9054
Aşırı Prematüre Bebeklerde Mortalite Öngörüsünde Umbilikal Kord Kan Gazı Parametrelerinin Değerlendirilmesi
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Original Article
VOLUME: 20 ISSUE: 2
P: 221-228
August 2022

Aşırı Prematüre Bebeklerde Mortalite Öngörüsünde Umbilikal Kord Kan Gazı Parametrelerinin Değerlendirilmesi

J Curr Pediatr 2022;20(2):221-228
DOI: 10.4274/jcp.2022.09821
Duran Yıldız
Ufuk Çakır
Ali Ulaş Tuğcu
Cüneyt Tayman
1. Sağlık Bilimleri Üniversitesi, Ankara Bilkent Şehir Hastanesi, Yenidoğan Yoğun Bakım Ünitesi, Ankara, Türkiye
No information available.
No information available
Received Date: 03.03.2022
Accepted Date: 15.04.2022
Publish Date: 31.08.2022
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ABSTRACT

Introduction:

Umbilical cord blood gas values at birth are the best method to show the acid-base balance of the newborn. While gas values in term and late preterm infants provide information about the clinical results of the newborn, the use of these values in premature infants is not clear. In this study, it was aimed to evaluate the relationship between umbilical cord blood gas values and mortality in preterm babies born at <29 weeks of gestation.

Materials and Methods:

Babies with a gestational age of <29 weeks were included in the study. Our study was carried out retrospectively. Umbilical cord gas (pH: power of hydrogen, pCO2: partial pressure of carbon dioxide, HCO3: bicarbonate, BE: base excess) values, demographic characteristics and clinical results were compared in the groups with and without mortality in the patients included in the study.

Results:

A total of 346 patients were included in the study, with 54 patients with mortality and 292 patients without mortality. According to our results, the mortality rate was 15.6% (54/346) in preterms with <29 weeks of gestation. Gestational week and birth weight were found to be lower in the group with mortality compared to the group without mortality (p<0.001, p<0.001, respectively). pH, HCO3 and BE were lower in patients with mortality compared to patients without mortality (p<0.001, p<0.001, p<0.001, respectively). Results were similar between the groups in terms of pCO2 values (p=0.270). Threshold pH value for mortality ≤7.18 [area under curve (AUC): 0.627], threshold HCO3 value ≤19.3 mmol/L (AUC: 0.950), and threshold BE value ≤-8.1 mmol/L (AUC: 0.969) was detected.

Conclusion:

HCO3 and BE are the most valuable parameters for mortality in umbilical cord blood gas in premature babies born with a gestational week <29.

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