Clinicopathological Analysis of Our Ten-Year Pediatric Percutaneous Kidney Biopsies
PDF
Cite
Share
Request
Original Article
P: 10-16
April 2022

Clinicopathological Analysis of Our Ten-Year Pediatric Percutaneous Kidney Biopsies

J Curr Pediatr 2022;20(1):10-16
1. İnönü Üniversitesi Tıp Fakültesi, Pediatrik Nefroloji Anabilim Dalı, Malatya, Türkiye
2. İnönü Üniversitesi Tıp Fakültesi, Patoloji Anabilim Dalı, Malatya, Türkiye
No information available.
No information available
Received Date: 03.01.2022
Accepted Date: 31.01.2022
Publish Date: 22.04.2022
PDF
Cite
Share
Request

ABSTRACT

Conclusion:

The high rate of compatibility between the histopathological diagnosis and our preliminary diagnoses should not question the necessity of pathological evaluation, and even all kinds of examinations should be used to reach the most accurate diagnosis with the contribution of genetic studies.

Results:

Of 126 patients who underwent kidney biopsy, 62 (49.2%) were male; 64 (50.8%) were girls; mean age was 9.5±4.1 years. The most common biopsy indication was nephrotic syndrome (32.5%). Immunoglobulin A nephropathy (IgAN) was the most common histopathological diagnosis (23%). The concordance between clinical preliminary diagnosis and histopathological diagnosis was as high as 82.6%.

Materials and Methods:

In our study, the files and biopsy results (a total of 134 biopsy results) of 126 pediatric patients aged 1-17 years who were followed up in our Pediatric Nephrology clinic and underwent percutaneous kidney biopsy between 2011 and 2021 were evaluated retrospectively. All patients’ age, gender, biopsy adequacy, compliance with the indication and histopathological diagnosis, and follow-up status were recorded.

Introduction:

Our aim in this study is to evaluate the data of native and transplant kidney biopsies in our tertiary pediatric nephrology center in terms of demographics and clinico-pathology, to determine biopsy indications and to evaluate the compatibility of indication and histopathological diagnosis.

References

1Pirani CL. Renal biopsy. An historical perspective. In: Silva FG, D’Agati VD, Nadasdy T, (eds). Renal Biopsy Interpretation, Churchill Livingstone: New York; 1996. p.1-19.
2Korbet SM. Percutaneous renal biopsy. Semin Nephrol 2002;22:254-67.
3Natalie SU, Mihail MS, Frederick JK. Renal Biopsy. In: Kher KK, Schnaper HW, Greenbaum LA, (eds). Clinical Pediatric Nephrology. 3th edition. Taylor & Francis Group; 2017. p.115-25.
4Yavaşcan Ö, Aksu N, Erdoğan H, Kara OD, Tuncel Çerçi T, Şen S, et al. Evaluation of percutaneous renal biopsy results in children: an eleven-year survey. J Turk Soc Nephrol 2005;14:195-201.
5Ergin M, Yavaşcan Ö, Serdaroğlu E, Ergin I, Diniz AG, Ortaç R. Dr. The clinic and histopathologıcal profıle of the renal biopsies evaluated between 2009-2010 at the pathology department of Dr. Behçet Uz Children’s Hospital. J Dr Behcet Uz Child Hosp 2011;1:51-7.
6Peru H, Elmacı AM, Karagöl C, Kara F. Evaluation of clinicopathological findings of 78 percutal renal biopsy. Selçuk Tıp Derg 2007;24:173-9.
7Printza N, Bosdou J, Pantzaki A, Badouraki M, Kollios K, Ghogha Ch, et al. Percutaneous ultrasound-guided renal biopsy in children: a singlecentre experience. Hippokratia 2011;15:258-61.
8Ding JJ, Lin SH, Huang JL, Wu TW, Hsia SH, Lin JJ, et al. Risk factors for complications of percutaneous ultrasound-guided renal biopsy in children. Pediatr Nephrol 2020;35:271-8.
9Garg AK, Kanitkar M, Venkateshwar V. Clinicopathological spectrum of renal biopsies in children. Med J Armed Forces India 2010;66:216-9.
10Santangelo L, Netti GS, Giordano P, Carbone V, Martino M, Torres DD, et al. Indications and results of renal biopsy in children: a 36-year experience. World J Pediatr 2018;14:127-33.
11Pilania RK, Venkatesh GV, Nada R, Vignesh P, Jindal AK, Suri D, et al. Renal Biopsy in Children-Effect on Treatment Decisions: A Single-Center Experience. Indian J Pediatr 2021;88:1036-9.
12Coppo R, Gianoglio B, Porcellini MG, Maringhini S. Frequency of renal diseases and clinical indications for renal biopsy in children. Nephrol Dial Transplant 1998;13:293-7.
13Riviera F, Gomez LJM, Garcia PR. Frequency of renalpathology in Spain 1994-1999. Nephrol Dial Transplant 2002;17:1594-602.
14Nation wide and long-term survey of primary glomerulonephritis in Japan as observed in 1,850 biopsied cases. Research Group on Progressive Chronic Renal Disease. Nephron 1999;82:205-13.
15HodFeins R, Tobar A, Davidovits M. Yield and complications of kidney biopsy over two decades in a tertiary pediatric center. Pediatr Int 2017;59:452-7.
Article is only available in PDF format. Show PDF
2024 ©️ Galenos Publishing House