ABSTRACT

Introduction:

In this study, it was aimed to evaluate the prenatal, natal and postnatal risk factors that premature babies may encounter and to determine the risk factors affecting this situation in babies with neurodevelopmental retardation.

Materials and Methods:

In this study, between February 2009 and February 2011, the files of 107 patients (53 girls, 54 boys) which were born before 37 weeks of gestation and continued their outpatient clinic controls in Dr. Behçet Uz Pediatrics Health and Surgery Training and Research Hospital were retrospectively scanned. Neurological examination, cranial MR (magnetic resonance imaging) and Bayley test results of the cases were evaluated.

Conclusions:

In the neurodevelopmental follow-up of premature babies, the presence of gestational diabetes, low weight gain and a reduce in head circumference growth, sepsis, anemia, and a low 5^th minute APGAR score were found to be important risk factors, it is important to protect babies from these risk factors for improved neurological development.

When the Bayley test is evaluated; it was determined that those who underwent mechanical ventilation, those who were administered surfactant, those who had convulsions, those with pathological neurological examination, those with EEG (electroencephalography) pathology, and those who remained in the intensive care unit had lower scores (p<0.05). In addition, with the increase in head circumference in the 2^nd month, the 6^th month psychomotor development index (PDI) score increased in the patients, and the 12^th month PDI also increased with the increase in the APGAR score (r>0.5 and p<0.05).

With cranial MR pathology; week of gestation (p=0.05), 5^th minute APGAR score (p=0.00), gestational diabetes (p=0.01), PDA (patent ductus arteriosus) closure treatment (p=0.02), sepsis (p=0.01), convulsion (p=0.03), anemia (p=0.01), and grade 3 and higher intracranial bleeding (p=0.00) were found to be significantly correlated.

Results:

In cases with pathological neurological examination; convulsions (p=0.02), hyperbilirubinemia (p=0.02) and cranial MR pathology (p=0.05) were more common, the increase in head circumference and weight gain in the 4^th week were less.

Keywords:

Head circumference, Bayley test, convulsion, neurodevelopment, prematurity

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Prematüre Bebeklerde Nörogelişimsel Risk Faktörleri

ABSTRACT

References