ABSTRACT

In this study, we observed that BPD development was higher in patients with low Hb concentrations measured at 1st and 7th days. We considered that Hb concentration might affect lung dynamics and respiratory system by means of different mechanisms. In conclusion, early preventive treatment might be started as determination of risky patients using the Hb concentrations at first days of life.

A total of 189 preterm infants were assessed according to exclusion criteria and 158 of them were investigated as 65 of them BPD and 93 of them non-BPD. In comparison of groups’ Hb concentrations, relationship was significant between 1st day and 7th day Hb concentrations of the BPD group (p<0.05). ROC analysis indicated that AUC of 1st day capillary Hb was 0.61 (p<0.05) and cut-off point optimized for sensitivity 55% and specificity %66 was determined as Hb level of 18mg/dl. ROC analysis indicated that AUC of 7st day Hb was 0.74 (p<0.05) and cut-off point optimized for sensitivity 86% and specificity 51% was determined as capillary Hb level of 16.3mg/dl (p<0.05).

In this retrospective cohort study, preterm infants <32weeks followed in our neonatal intensive care unit were included. Patients diagnosed as BPD were categorized as group 1 where others were as group 2. Capillary Hb levels were collected at 1st, 7th and 14th day of their life.

Bronchopulmonary dysplasia (BPD) is a common preterm chronic lung disease. Objective of the study was to investigate relationship of BPD and hemoglobin (Hb) concentrations in preterms.