Neonatal kolestaz, serum direk bilirubin seviyelerinin hayatin ilk 14 gününden sonra da yüksek seyretmesi ile karakterize durumdur. Yenidoganda kolestaz genetik, enfeksiyöz, metabolik veya safra akiminin mekanik olarak obstruksiyonuna ve hepatik ekskretuar sistemde bozukluklara sebep olan henüz tanimlanamamis bazi nedenlere bagli olabilir. Servisimize bir yillik sürede direk hiperbilirubinemi ön tanisiyla yatan ve yapilan incelemeler sonucunda neonatal kolestaz saptanan olgular incelendi. Hastalarin tani sonrasi progresyonlari ve cerrahi sonuçlari degerlendirildi. Toplam 9 hastanin E/K orani 1/2 idi.Tani yaslari 20 ile180 gün arasindaydi (Ortalama 100 gün). 3 hastada (%33) idiopatik neonatal hepatit, 1 hastada (%11) Byler hastaligi, 5 hastada (%56) bilier atrezi tespit edildi. Bilier atrezi tanisi alan tüm hastalar cerrahi operasyona alinmak üzere hastanemiz Çocuk Cerrahisine devredildi. Diger 4 hasta Gastroenteroloji Bölümünce takibe alindi. Cerrahi operasyon planlanan hastalardan biri operasyonu kabul etmedi. 3 hastaya Kasai operasyonu, 1 hastaya koledok atrezisi nedeniyle hepatojejunostomi ve Roux&Y enterostomi uygulandi. Idiopatik neonatal hepatit tanisi alan hastalardan birine, karaciger transplantasyonu planlandi, uygun transplantasyon merkezine devredildi.
Neonatal Kolestaz Olgularimiz - POSTER: 51
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Neonatal Kolestaz Olgularimiz - POSTER: 51
J Curr Pediatr 2005;3(1)
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- 1Dr.Behçet Uz Çocuk Hastaliklari Ve Çocuk Cerrahisi Egitim Ve Arastirma Hastanesi, Izmir
- 2Dr. Behçet Uz Çocuk Hastaliklari Ve Cerrahisi Egitim Ve Arastirma Hastanesi, Izmir
- 3Dr. Sami Ulus Çocuk Sagligi Ve Hastaliklari Egitim Ve Arastirma Hastanesi, Izmir
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