Gluten enteropatisi (Çölyak hastaligi) proksimal ince barsagi tutan ve glutene karsi kalici intolerans ile karakterize bir enteropatidir. Patogenezde çevresel, genetik ve immunolojik faktörler rol oynar. Hastalik kronik ishal, malabsorbsiyon, distansiyon gibi daha sik karsilasilan yakinmalar olmakla birlikte, tedaviye cevap vermeyen anemi, boy kisaligi, puberte gecikmesi, ödem gibi atipik bulgularla da karsimiza çikabilmektedir.Özellikle son yillarda serolojik testler gluten enteropati süphesi olan hastalarin tanisinda ve glutensiz diyete alinan yanitin degerlendirilmesinde kullanilmaktadir. Bu olguda kilo kaybi, pretibial ve bifissür tarzinda ödem yakinmasiyla basvuran, serum protein ve albümin düzeylerinin düsük olan, serolojik testlerinde antigiadin Ig A, IgG ve endomisial antikoru pozitif bulunan, histopatolojik bulgularla Çölyak hastaligi tanisi alan 4 yasindaki kiz çocugu sunulmustur.Bu olgu nedeniyle malabsorbsiyon sendromlarindan birisi olan gluten enteropatisinin sadece anemi, kilo kaybi ve ödem ile basvurabilecegine dikkat çekilmek istenmistir.
Hipoproteinemi ve Anemi ile Basvuran Bir Atipik Gluten Enteropati Olgusu - POSTER: 52
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Hipoproteinemi ve Anemi ile Basvuran Bir Atipik Gluten Enteropati Olgusu - POSTER: 52
J Curr Pediatr 2005;3(1)
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- 1Karaelmas Üniversitesi Tip Fakültesi, Pediatri Anabilim Dali, Zonguldak
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